Associate Scientist


Job description:

The Associate Scientist will report to the Associate Director in the Research and Drug Discovery group. The candidate will be responsible for designing and executing experimental systems for functional validation of novel immunomodulatory molecules discovered by Compugen, including target validation activities, research tools generation and QC, expression studies, Abs characterization, cell-based assays, and reporter assay. The candidate will be responsible for planning and conducting experiments, recording and analyzing data, presenting results to management, and writing research reports. The candidate is expected to demonstrate creative/out of the box thinking, propose original solutions to complex problems, perform hands-on experimental work and be an excellent team player.

Generate over expression systems and knock-down/knockout cells
Perform different biochemical assays for antibody characterization (Western blot, ELISA)
Perform cell based functional assays
Perform antibody based in vitro assays
Record results in laboratory notebook, prepare written reports and oral presentations in a timely manner
Collaborate with team members to ensure timely progress of research projects according to the pipeline prioritization
Temporary position for a year

Required qualifications:

PhD in Life Sciences or MSc in Life Sciences and 2 years of experience in the biotech industry
Highly experienced in cell culture technologies – must
Over expression systems (lentivirus, retrovirus, transfections etc.) including single clone generation and characterization, cell soring
Knock-down/knock out technologies (si/shRNA, CRISPR)
Extensive experience in cell based in vitro assays – must
Experience in FACS staining
Antibody based in vitro assays
Cell based functional assays
Experience in molecular biology methods –an advantage
Experience biochemical technologies – Western blot, ELISA – an advantage
Knowledgeable in monoclonal Ab Discovery – advantage
Experience and knowledge in protein purification, QC and analytics – an advantage
Excellent written and verbal communication skills (English)
Ability to prioritize and manage multiple projects and activities
Ability to work independently; proactively addresses issues and troubleshoot problems

Job location